Patrick J McNamara Selected Research

Y 27632

6/2015	Rho kinase mediates right ventricular systolic dysfunction in rats with chronic neonatal pulmonary hypertension.
1/2014	Rho-kinase inhibitor prevents bleomycin-induced injury in neonatal rats independent of effects on lung inflammation.
12/2010	Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension.
2/2008	Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide.

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Patrick J McNamara Research Topics

Disease

29	Patent Ductus Arteriosus 06/2022 - 01/2010
22	Pulmonary Hypertension 04/2022 - 09/2005
15	Hypoxia (Hypoxemia) 01/2021 - 09/2005
15	Hypotension (Low Blood Pressure) 01/2021 - 04/2006
10	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2021 - 03/2011
8	Lung Diseases (Lung Disease) 06/2022 - 01/2010
6	Bronchopulmonary Dysplasia 09/2021 - 07/2012
6	Lung Injury 12/2017 - 09/2005
6	Vascular Remodeling 03/2015 - 11/2006
5	Hypercapnia 04/2014 - 11/2006
4	Birth Weight (Birth Weights) 06/2022 - 06/2006
4	Hypothermia 01/2020 - 08/2011
4	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2018 - 04/2014
4	Right Ventricular Hypertrophy 01/2014 - 12/2010
3	Necrotizing Enterocolitis 09/2021 - 01/2017
3	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 02/2006
3	Inflammation (Inflammations) 03/2015 - 07/2012
3	Low Cardiac Output 05/2014 - 04/2012
3	Acidosis 01/2010 - 04/2006
2	Hypertension (High Blood Pressure) 09/2021 - 02/2006
2	Brain Injuries (Brain Injury) 01/2021 - 05/2014
2	Alcoholism (Alcohol Abuse) 01/2019 - 04/2011
2	Acute-Phase Reaction 01/2018 - 01/2006
2	Sepsis (Septicemia) 01/2017 - 04/2014
2	Heart Arrest (Cardiac Arrest) 06/2014 - 02/2006
2	Hemorrhage 04/2014 - 04/2014
2	Congenital Heart Defects (Congenital Heart Defect) 03/2010 - 01/2010
1	Edema (Dropsy) 06/2022
1	Critical Illness (Critically Ill) 04/2022
1	Brain Diseases (Brain Disorder) 01/2022
1	Left Ventricular Dysfunction 09/2021
1	Intestinal Perforation 09/2021
1	Renal Insufficiency (Renal Failure) 09/2021
1	Vascular Malformations 02/2021
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2021
1	Hypovolemia 01/2021
1	Hyponatremia 01/2021
1	Disease Progression 01/2021
1	Wounds and Injuries (Trauma) 01/2019
1	Meconium Aspiration Syndrome 01/2018
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018
1	Obesity 01/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018
1	Atherosclerosis 01/2018
1	Diabetes Mellitus 01/2018
1	Ventilator-Induced Lung Injury 12/2017

Drug/Important Bio-Agent (IBA)

12	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2021 - 09/2005
8	Milrinone (Primacor)FDA LinkGeneric 01/2021 - 06/2006
6	rho-Associated KinasesIBA 06/2015 - 02/2008
5	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2019 - 08/2010
4	Vasopressins (Vasopressin)IBA 04/2022 - 02/2014
4	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 04/2012
4	Acetaminophen (Paracetamol)FDA LinkGeneric 09/2021 - 09/2014
4	Y 27632IBA 06/2015 - 02/2008
4	Bleomycin (Blenoxane)FDA LinkGeneric 03/2015 - 02/2008
4	Peroxynitrous Acid (Peroxynitrite)IBA 04/2014 - 11/2009
3	Oxygen (Dioxygen)IBA 01/2021 - 09/2005
3	Epinephrine (Adrenaline)FDA LinkGeneric 06/2014 - 02/2006
3	Hydromorphone (Dilaudid)FDA LinkGeneric 01/2004 - 02/2003
2	Biological ProductsIBA 06/2022 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 08/2021 - 01/2017
2	Sildenafil Citrate (Viagra)FDA Link 01/2021 - 01/2014
2	Surface-Active Agents (Surfactants)IBA 06/2016 - 01/2010
2	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 06/2015 - 11/2010
2	fasudil (AT 877)IBA 06/2015 - 02/2008
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2014 - 07/2012
2	CytokinesIBA 04/2014 - 07/2012
2	Vasodilator Agents (Vasodilators)IBA 01/2014 - 02/2008
2	Pharmaceutical PreparationsIBA 04/2011 - 01/2006
2	3-nitrotyrosineIBA 11/2010 - 11/2010
2	Vasoconstrictor AgentsIBA 09/2005 - 01/2004
1	boldenone undecylenate (Equipoise)IBA 06/2022
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 09/2021
1	Enalapril FDA LinkGeneric 09/2021
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 09/2021
1	Cyclooxygenase InhibitorsIBA 09/2021
1	ElectrolytesIBA 01/2021
1	Tranexamic Acid (AMCA)FDA Link 01/2021
1	Phenobarbital (Luminal)FDA Link 01/2020
1	Lidocaine (Xylocaine)FDA LinkGeneric 01/2019
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2019
1	Indomethacin (Indometacin)FDA LinkGeneric 06/2018
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2018
1	Apolipoproteins B (ApoB)IBA 01/2018
1	Lipoproteins (Lipoprotein)IBA 01/2018
1	LipidsIBA 01/2018
1	Proteoglycans (Proteoglycan)IBA 01/2018
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2018

Therapy/Procedure

21	Ligation 06/2022 - 01/2007
11	Induced Hypothermia 01/2022 - 03/2011
11	Therapeutics 09/2021 - 09/2005
5	Artificial Respiration (Mechanical Ventilation) 11/2019 - 02/2006
4	Mechanical Ventilators (Ventilator) 01/2020 - 04/2006
2	Rewarming 12/2019 - 01/2018
2	Critical Care (Surgical Intensive Care) 01/2018 - 08/2011
2	Intravenous Infusions 01/2004 - 01/2004
1	High-Frequency Jet Ventilation 01/2022
1	Precision Medicine 01/2021
1	Drug Therapy (Chemotherapy) 01/2018
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 12/2017